Fluoride
Dibasic, Monobasic, Monohydrate, Phosphate (fluoride) is a small molecule pharmaceutical. Fluoride was first approved as Sodium phosphates in plastic container on 1983-05-10.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Sodium fluoride
+
Triclosan
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| COLGATE TOTAL | Colgate-Palmolive | N-020231 DISCN | 1997-07-11 | 1 products, RLD |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| 2080 k ginger mint | OTC monograph final | 2017-01-10 |
| 2080 k herbal mint | OTC monograph final | 2017-01-10 |
| 2080 k original | OTC monograph final | 2017-04-26 |
| 365 whole foods market anticavity/antigingivitis mouthwash | OTC monograph not final | 2022-05-12 |
| 365 whole foods market spearmint flavored fluoride mouthwash anticavity | C200263 | 2026-05-04 |
| 365 whole foods spearmint flavored fluoride mouthwash anticavity | C200263 | 2026-05-01 |
| 3ecare dual formula whiteningtoothpaste refill | C200263 | 2026-04-23 |
| 3ecare dual formulawhiteningtoothpaste | C200263 | 2026-06-02 |
| 3seconds magic gargle lemon | OTC monograph final | 2020-02-09 |
| 3seconds magic gargle peach | OTC monograph final | 2020-02-10 |
Show 1139 more
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| bacterial infections and mycoses | — | D001423 | — |
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent | Expires | Flag | FDA Information |
|---|---|---|---|
| Sodium Phosphate, Dibasic, Anhydrous / Sodium Phosphate, Monobasic, Monohydrate, Osmoprep, Salix Pharms | |||
| 7687075 | 2028-06-22 | DS, DP | |
ATC Codes
A: Alimentary tract and metabolism drugs
— A01: Stomatological preparations
— A01A: Stomatological preparations
— A01AA: Caries prophylactic agents
— A01AA01: Sodium fluoride
— A01AA04: Stannous fluoride
— A01AA51: Sodium fluoride, combinations
— A12: Mineral supplements
— A12C: Other mineral supplements in atc
— A12CD: Fluoride supplements
— A12CD01: Sodium fluoride
— A12CD51: Fluoride, combinations
V: Various drug classes in atc
— V09: Diagnostic radiopharmaceuticals
— V09I: Tumour detection radiopharmaceuticals
— V09IX: Other diagnostic radiopharmaceuticals for tumour detection in atc
— V09IX06: Sodium fluoride (18f)
Clinical
Clinical Trials
1226 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dental caries | D003731 | EFO_0003819 | K02 | 33 | 42 | 53 | 44 | 249 | 407 |
| Dentin sensitivity | D003807 | — | — | 7 | 17 | 25 | 13 | 95 | 150 |
| Gingivitis | D005891 | — | K05.10 | 3 | 7 | 29 | 25 | 60 | 123 |
| Hypersensitivity | D006967 | EFO_0003785 | T78.40 | 6 | 20 | 21 | 12 | 70 | 120 |
| Dental plaque | D003773 | — | — | 1 | 4 | 26 | 6 | 49 | 86 |
| Prostatic neoplasms | D011471 | — | C61 | 7 | 11 | 4 | 2 | 13 | 37 |
| Molar hypomineralization | D000094604 | — | — | 1 | 3 | 2 | 1 | 20 | 25 |
| Oral hygiene | D009910 | — | — | 1 | 3 | — | 1 | 19 | 24 |
| Dental enamel hypoplasia | D003744 | EFO_1001304 | — | 2 | 4 | 2 | 1 | 16 | 22 |
| Periodontal diseases | D010510 | — | K05.6 | — | — | 8 | 5 | 8 | 21 |
Show 41 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Tooth erosion | D014077 | — | K03.2 | — | 2 | 5 | — | 9 | 16 |
| Healthy volunteers/patients | — | — | — | 3 | 1 | 1 | — | 8 | 13 |
| Lung neoplasms | D008175 | — | C34.90 | 6 | 2 | 1 | — | 2 | 10 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 4 | 3 | 1 | — | 2 | 9 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 1 | 1 | — | 7 | 9 |
| Gingival hemorrhage | D005884 | — | — | — | — | 2 | — | 5 | 7 |
| Mucositis | D052016 | EFO_1001898 | — | — | 1 | 1 | — | 4 | 6 |
| Colorectal neoplasms | D015179 | — | — | 2 | 1 | 1 | — | 2 | 6 |
| Heart arrest | D006323 | EFO_0009492 | I46 | 1 | — | 1 | — | 4 | 6 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 1 | — | 5 | 6 |
Show 36 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 7 | 1 | — | — | 8 | 16 |
| Root caries | D017213 | EFO_1001163 | — | 3 | 1 | — | — | 13 | 16 |
| Fissure in ano | D005401 | — | K60.2 | — | 1 | — | — | 14 | 15 |
| Glioma | D005910 | EFO_0000520 | — | 5 | 3 | — | — | 2 | 10 |
| Glioblastoma | D005909 | EFO_0000515 | — | 4 | 2 | — | — | 1 | 7 |
| Brain neoplasms | D001932 | EFO_0003833 | C71 | 3 | 1 | — | — | 2 | 6 |
| Non-small-cell lung carcinoma | D002289 | — | — | 4 | 1 | — | — | 2 | 6 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 3 | 1 | — | — | 1 | 5 |
| Carotid stenosis | D016893 | — | — | — | 1 | — | — | 4 | 5 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | 2 | 3 |
Show 49 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Halitosis | D006209 | — | R19.6 | 1 | — | — | — | 7 | 8 |
| Head and neck neoplasms | D006258 | — | — | 1 | — | — | — | 5 | 6 |
| Colonic neoplasms | D003110 | — | C18 | 2 | — | — | — | 1 | 3 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | — | — | — | 1 | 3 |
| Gliosarcoma | D018316 | — | — | 2 | — | — | — | 1 | 3 |
| Ependymoma | D004806 | — | — | 2 | — | — | — | 1 | 3 |
| Astrocytoma | D001254 | EFO_0000271 | — | 2 | — | — | — | 1 | 3 |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 2 | — | — | — | 1 | 3 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 1 | — | — | — | 2 | 3 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | 1 | — | — | — | 2 | 3 |
Show 65 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Stomatitis | D013280 | EFO_1001904 | K12.1 | — | — | — | — | 4 | 4 |
| Dental anxiety | D016854 | — | — | — | — | — | — | 4 | 4 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | — | — | — | 3 | 3 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | — | — | 3 | 3 |
| Hernia | D006547 | — | K40-K46 | — | — | — | — | 3 | 3 |
| Mouth diseases | D009059 | EFO_1001047 | K13 | — | — | — | — | 3 | 3 |
| Health education | D006266 | — | — | — | — | — | — | 3 | 3 |
| Central nervous system neoplasms | D016543 | — | — | — | — | — | — | 2 | 2 |
| Schizophrenia | D012559 | EFO_0000692 | F20 | — | — | — | — | 2 | 2 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 2 | 2 |
Show 165 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Fluoride |
| INN | pegamotecan |
| Description | Fluorine F-18, Sodium Fluoride F 18 (fluoride) is a small molecule pharmaceutical. Fluoride was first approved as Fluorine F-18 on 1982-01-01. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | F |
Identifiers
| PDB | — |
| CAS-ID | 7664-39-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1232767 |
| ChEBI ID | 29228 |
| PubChem CID | 28179 |
| DrugBank | — |
| UNII ID | ZY7ZTE7LFH (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Fluoride
+
Fluoride ion
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 195,301 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
6,118 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use